Inflammation Causes Vitamin B6 Deficiency

Inflammation causes Vitamin B6 deficiency.

Tendonitis and Carpal Tunnel and Whiplash all cause Inflammation.

Vitamin B6 insufficiency/deficiency can cause muscle pain and nerve pain.

So if you are suffering from Wrist Tendonitis, or Tennis Elbow, or -any- physical problem where Inflammation is a factor, you just may want to consider that Vit B6 deficiency might be adding to your pain symptoms.

Even if you don't think B6 is involved, a bottle of Vit B6 is under $10, so there's no reason not to make sure your body has what it needs.


Inflammation Causes B6 Deficiency
Research Shows That....

There are lots of research studies out there that correlate vitamin B6 deficiency with elevated levels of Inflammation markers. And whether the studies are on rhemumatoid arthritis or heart conditions or Carpal Tunnel or thrombosis, studies on humans and (unfortunately) animals are consistent in this.

Below are just two studies I have added as reference towards the concept that Inflammation causes Vitamin B6 deficiency.

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This study observes low levels of B6 in the presence of C-Reactive Protein (also called CRP) which is a marker of an active inflammation process in the body.

Study: Low Circulating Vitamin B6 Is Associated With Elevation of the Inflammation Marker C-Reactive Protein...

Researchers that previously identified decreased levels of circulating B6 did a new study and found that inflammation can cause tissue specific depletion. It also observes that Vit B6 depletion is present with the elevated C-Reactive Protein markers of Inflammation.

Study: Inflammation causes tissue-specific depletion of vitamin B6





Inflammation Causes B6 Deficiency
But B6 Doesn't Reduce Inflammation

It's clear from the research that's out there that Inflammation causes Vitamin B6 deficiency.

It's also clear that B6 -sufficiency- DOES NOT reduce inflammation.

Inflammation is a primary cause of pain with Tendonitis and Carpal Tunnel Syndrome.

So if you have Tendonitis or Carpal Tunnel, you definitely have a Process of Inflammation.

This means we need to start considering the idea that inflammation is causing a Vit B6 deficiency that is contributing to your pain.

Unfortunately, supplementing with Vitamin B6, both to get your body to -sufficient- levels and above, does NOT beneficially affect the inflammation process.

The inflammation process uses up Vit B6, but Vitamin B6 supplementation does not reduce Inflammation. But it can/will reduce pain.


This study is reference to pyridoxine (Vitamin B6) supplementation correcting the deficiency but not reducing the inflammation.

Study: Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation


To make that really clear:

  • The Inflammation process eats up Vitamin B6
  • Lack of B6 causes pain (that mimics carpal tunnel and tendonitis symptoms)
  • Taking B6 doesn't reduce the inflammation process, but does reduce pain caused by B6 insufficiency.


Inflammation Causes Vitamin B6 Deficiency
Sufficiency And Beyond

Researched and documented safe and effective levels of B6 supplementation are 100-300mg/day.  More is also safe and effective, but it depends on your situation, symptoms/issues, and your nutritional needs.


Filling up any insufficiency or deficiency can help reduce your pain levels. 

To be clear, taking B6 can alleviate any pain/problem that is CAUSED by lack of Vit B6.

But remember, this doesn't directly affect your inflammation process, and that process is going to continue to eat up B6.  So deal with the causes of inflammation and the side effects of inflammation.


As long as you have inflammation (and everybody does, locally and/or systemically), it may be wise to supplement with Pyridoxine (B6).


Interestingly enough, research shows that even people that do not have B6 deficiency ALSO benefit from Vitamin B6 supplementation.





Return to the top of this Inflammation Causes Vitamin B6 Deficiency page. 

Go to the Process of Inflammation page. 

Go to the main Tendonitis page. 

Go to the TendonitisExpert.com homepage,








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